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MCT4 (SLC16A3) Antibody (AMT-014-200UL) in WB
Western blot analysis of human K562 chronic myelogenous leukemia cell line lysate (lanes 1 and 3) and human MDA-MB-231 breast adenocarcinoma cell line lysate (lanes 2 and 4): - 1,2. Anti-MCT4 (SLC16A3) Antibody (#AMT-014), (1:200).3,4. Anti-MCT4 (SLC16A3) Antibody , preincubated with MCT4/SLC16A3 Blocking Peptide (#BLP-MT014).
产品信息
AMT-014-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)REVEHFLKAEPEK, corresponding to amino acid residues 447-459 of rat MCT4, Intracellular, C-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MCT 3; MCT 4; MGC138472; MGC138474; monocarboxylate transporter; Monocarboxylate transporter 3; Monocarboxylate transporter 4; MOT4; solute carrier family 16 (monocarboxylate transporter), member 3; solute carrier family 16 (monocarboxylic acid transporters), member 3; Solute carrier family 16 member 3; solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
基因别名: MCT 3; MCT 4; MCT-3; MCT-4; MCT3; MCT4; SLC16A3
UniProt ID: (Human) O15427, (Mouse) P57787, (Rat) O35910
Entrez Gene ID: (Human) 9123, (Mouse) 80879, (Rat) 80878
