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Immunogen sequence: NSGSVLDYFSE RSNPFYDRTC NNEVVKMQRL TLEHLNQMVG IEYILLHAQE PILFIIRKQQ RQSPAQVIPL ADYYIIAGVI YQAPDLGSVI NSRVLTAVHG IQSAFDEAMS YCRYHPSKGY WWHFKDHEEQ DKVRPKAKRK EEPSSI
Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.
MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activator-recruited cofactor 33 kDa component; ARC33; CTD-2540L5.5; hMed6; Mediator complex subunit 6; Mediator of RNA polymerase II transcription subunit 6; Renal carcinoma antigen NY-REN-28
基因别名: ARC33; MED6; NY-REN-28
UniProt ID: (Human) O75586
Entrez Gene ID: (Human) 10001