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MGST2 Antibody (PA5-106675) in ICC/IF
Immunocytochemistry analysis of MGST2 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with MGST2 polyclonal antibody (Product # PA5-106675) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-106675
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human MGST2(Accession Q99735), corresponding to amino acid residues Y21-G71.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2854343
产品详细信息
Antibody detects endogenous levels of total MGST2.
靶标信息
MGST2 (Microsomal glutathione S-transferase 2) is a 147 amino acid protein encoded by the human gene MGST2. MGST2 can catalyze the production of LTC4 (leukotriene C4) from LTA4 (leukotriene A4) and reduced glutathione. It can also catalyze the conjugation of 1-chloro-2,4-dinitrobenzene with reduced glutathione. MSGT2 is a multi-pass membrane protein found as a homodimer. MGST2 belongs to the MAPEG family and is expressed in liver, spleen, skeletal muscle, heart, adrenals, pancreas, prostate, testis, fetal liver, and fetal spleen. It has very low expression in lung, brain, placenta and bone marrow. Also, MGST2 is the only GST expressed in human umbilical vein endothelial cells (HUVECs).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ27438; Glutathione peroxidase MGST2; Leukotriene C4 synthase MGST2; MGC14097; Microsomal glutathione S-transferase 2; Microsomal glutathione S-transferase II; Microsomal GST-2; Microsomal GST-II
基因别名: GST2; MGST-II; MGST2
UniProt ID: (Human) Q99735, (Mouse) A2RST1
Entrez Gene ID: (Human) 4258, (Rat) 295037, (Mouse) 211666
glutathione biosynthetic process
xenobiotic metabolic process
response to organonitrogen compound
leukotriene biosynthetic process
response to lipopolysaccharide
positive regulation of catalytic activity
oxidation-reduction process
cellular oxidant detoxification
glutathione derivative biosynthetic process
