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产品信息
PA5-63743
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644314
产品详细信息
Immunogen sequence: LVEEHGSVHN LSLPESTLLQ AVTNTQVIDG FFVKRTADIK ESAAYLALLT RGLQRLYQGH TLRSRPWGTP GNPESGAMTS PNPLCSLLTF SDFNAGAIKN KAQSVREVFA RQLMQVRGVS GEKAAALVDR YSTPA
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
靶标信息
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81 endonuclease homolog; SLX3 structure-specific endonuclease subunit homolog
基因别名: MUS81; SLX3
UniProt ID: (Human) Q96NY9
Entrez Gene ID: (Human) 80198
