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Unconventional myosin that functions as actin-based motor protein with ATPase activity. Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes. Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: myosin 1C; Myosin heavy chain myr 4; myosin IC; myosin-Id; myosin1C; Unconventional myosin from rat 4 for myosin I heavy chain; Unconventional myosin-Id
基因别名: Myo1c; Myo1d; Myr2; Myr4
UniProt ID: (Rat) Q63357
Entrez Gene ID: (Rat) 25485