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NF-H Antibody (OMA1-06117) in ICC/IF
JOR spine 2020 -
FIGURE 7 ""Sholl"" analysis of DRG neurons cultured at 2% and 20% oxygen for 2 days. A,B, Pattern images of DRG neurons (immunofluorescent staining with NF-200 antibody). C, Schematic showing the ""Sholl"" analysis of the outgrowth pattern. Circled samplings intersect with the neurite arbors providing information on how far the outgrowth can reach (represented as ending radius) and the number of branches (r... View More
产品信息
OMA1-06117
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Dog,
Chicken,
Guinea pig,
Hamster,
Human,
Mouse,
Non-human primate,
Sheep,
Rabbit,
Rat,
Xenopus,
Zebrafish
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
RNF 405
抗原
Neurofilament preparation of calf brain tissue
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_325538
产品详细信息
OMA1-06117 reacts exclusively with the phosphorylated form of the 200 kDa neurofilament from human, mouse, rat, canine, rabbit, monkey, bovine, ovine, hamster, chicken, guinea pig, and Xenopus laevis tissues.
OMA1-06117 has been successfully used in Western blot and IHC (P) procedures. By Western blot, this antibody detects a single ~200 kDa protein representing phosphorylated neurofilament from rat brain homogenate.
OMA1-06117 antigen is cytoskeletal preparation of calf brain tissue.
靶标信息
Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 200 kDa neurofilament protein; heavy neurofilament protein; intermediate filament protein; NEF3; neurofilament; neurofilament 200kDa; Neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide 200kDa-like; neurofilament, heavy polypeptide L homeolog; NF 200 kD; NF-H; NHC
基因别名: CMT2CC; I79_012512; KIAA0845; mKIAA0845; NEFH; NF-H; NF200; NFH; XELAEV_18007418mg
UniProt ID: (Human) P12036, (Mouse) P19246
microtubule cytoskeleton organization
ovarian follicle atresia
axonogenesis
spinal cord development
hippocampus development
cerebral cortex development
cell projection assembly
axon regeneration
neurofilament bundle assembly
cellular response to oxidative stress
response to cocaine
peripheral nervous system neuron axonogenesis
axon development
cellular response to estradiol stimulus
regulation of organelle transport along microtubule
response to sodium arsenite
response to acrylamide
brain development
embryo development
neuron projection development
intermediate filament cytoskeleton organization
intermediate filament bundle assembly
neurofilament cytoskeleton organization
