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NFYA Antibody (MA5-36198) in ICC/IF
Immunofluorescence analysis of NFYA was performed using 70% confluent log phase A-431 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with NFYA Recombinant Rabbit Monoclonal Antibody (JE54-87) (Product # MA5-36198) at 1:100 dilution in 0.1% BSA, incubated at 4 degrees celsius overnight, and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluo... View More
产品信息
MA5-36198
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JE54-87
抗原
Synthetic peptide within Human NFYA aa 298-347
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 0.05% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2890476
靶标信息
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAAT box DNA-binding protein subunit A; CAAT-box DNA binding protein subunit A; CAAT-box DNA-binding protein subunit A; CBF-A; CBF-B; CCAAT-binding transcription factor subunit A; CCAAT-binding transcription factor subunit B; FLJ11236; HAP2 CCAAT-binding protein; nf-y; NF-YA; Nuclear transcription factor Y subunit A; Nuclear transcription factor Y subunit alpha; nuclear transcription factor Y, alpha; Transcription factor NF-Y, A subunit
基因别名: AA407810; CBF-A; CBF-B; HAP2; NF-YA; NFYA; SEZ-10; SEZ10
UniProt ID: (Human) P23511, (Mouse) P23708, (Rat) P18576
Entrez Gene ID: (Human) 4800, (Mouse) 18044, (Rat) 29508
core promoter sequence-specific DNA binding
transcription cofactor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
transcription regulatory region DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor binding
DNA-binding transcription factor
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of transcription, DNA-templated
rhythmic process
transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of stem cell population maintenance
positive regulation of stem cell proliferation
