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This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: angiotensin binding protein; Angiotensin-binding protein; endopeptidase 24.16; MEP; Microsomal endopeptidase; Mitochondrial oligopeptidase M; neurolysin (metallopeptidase M3 family); Neurolysin, mitochondrial; Neurotensin endopeptidase
基因别名: 4930472G13Rik; AGTBP; C79345; EP24.16; KIAA1226; MEP; MOP; NLN
UniProt ID: (Human) Q9BYT8, (Mouse) Q91YP2, (Rat) P42676
Entrez Gene ID: (Dog) 478081, (Human) 57486, (Mouse) 75805, (Rat) 117041