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Immunogen sequence: MAPVEHVVAD AGAFLRHAAL QDIGKNIYTI REVVTEIRDK ATRRRLAVLP YELRFKEPLP EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV SHLKQEPQKV KVSSSIQHPE TPLHISGFHL PYKPKPPQET EKGHSACEPE NLEFSSFMFW RNPLPNIDHE LQELLIDRGE DVPSEEEEEE ENGFEDRKDD SDDDGGGWIT PSNIKQIQQE LEQCDVPEDV
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: adenocarcinoma antigen recognized by T lymphocytes 4; nin one binding protein; NIN1/RPN12 binding protein 1 homolog; Phosphorylation regulatory protein HP-10; Protein ART-4; PSMD8 binding protein 1; RNA-binding protein NOB1
基因别名: 1700021I09Rik; ART-4; ART4; MST158; MSTP158; NOB1; NOB1P; PSMD8BP1
UniProt ID: (Human) Q9ULX3, (Rat) Q6VEU1, (Mouse) Q8BW10
Entrez Gene ID: (Human) 28987, (Rat) 291996, (Mouse) 67619