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产品信息
PA5-51463
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Dog
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644765
产品详细信息
Immunogen sequence: PVQFKDCGSV DGVIKEVNVS PCPTQPCQLS KGQSYSVNVT FTSNIQSKSS KAVVHGILMG VPVPFPIPEP DGCKSGINCP IQKDKTYSYL NKLPVKSEYP SIKLVVEWQL QDDKNQSLFC WEIPVQIVSH
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.
靶标信息
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: epididymal protein 1; epididymal secretory protein 1; Epididymal secretory protein E1; He1; Human epididymis-specific protein 1; mE1; MGC1333; Niemann Pick type C2; Niemann Pick type C2 protein homolog; Niemann-Pick disease type C2 protein; Niemann-Pick disease, type C2; NP-C2; NPC intracellular cholesterol transporter 2; tissue-specific secretory protein
基因别名: 2700012J19Rik; AA408070; AU045843; EDDM1; HE1; NPC2; re1
UniProt ID: (Human) P61916, (Mouse) Q9Z0J0
Entrez Gene ID: (Human) 10577, (Mouse) 67963, (Rat) 286898
cholesterol metabolic process
response to virus
phospholipid transport
regulation of isoprenoid metabolic process
cholesterol transport
intracellular sterol transport
intracellular cholesterol transport
cholesterol efflux
cholesterol homeostasis
glycolipid transport
lipid metabolic process
steroid metabolic process
biological_process
