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产品信息
MA5-14827
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
S.902.7
抗原
Synthetic peptide corresponding to residues surrounding Ala217 of human Naked2
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
<0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_10986959
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for processing of TGFA and for targeting of TGFA to the basolateral membrane of polarized epithelial cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dvl-binding protein NKD2; hNkd2; naked cuticle-2; Naked-2; Protein naked cuticle homolog 2
基因别名: Naked2; NKD2
UniProt ID: (Human) Q969F2
Entrez Gene ID: (Human) 85409
exocytosis
positive regulation of protein processing
Wnt signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Golgi vesicle fusion to target membrane
protein targeting to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
negative regulation of canonical Wnt signaling pathway
