Invitrogen

ORAI1 Monoclonal Antibody (6D11A11)

ORAI1 Antibody in Immunohistochemistry (IHC)

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ORAI1 Antibody (MA5-15777) in IHC

Immunohistochemistry of ORAI1 in human spleen tissue with ORAI1 Monoclonal Antibody (6D11A11) (Product # MA5-15777) at 2.5 µg/mL.

ORAI1 Antibody in Western Blot, Immunocytochemistry (WB, ICC/IF)

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产品信息

MA5-15777

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

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免疫组化 (IHC)

2.5 µg/mL

免疫细胞化学 (ICC/IF)

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

6D11A11

抗原

A 16 amino acid peptide from near the carboxy terminus of human ORAI1.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_11154170

产品详细信息

A suggested positive control is human spleen tissue lysate.

靶标信息

ORAI1 is a plasma membrane protein essential for store-operated calcium entry.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The Role of Orai1 in Regulating Sarcoplasmic Calcium Release, Mitochondrial Morphology and Function in Myostatin Deficient Skeletal Muscle.

Frontiers in physiology

Sztretye M,Singlár Z,Balogh N,Kis G,Szentesi P,Angyal Á,Balatoni I,Csernoch L,Dienes B

MA5-15777 was used in Western Blotting to show that reduced function and/or expression of SOCE partners (in this study Orai1) and mitochondrial defects could play an important role in muscle weakness and degeneration associated with certain pathologies, perhaps including loss of function of the neuromuscular junction and aging..

Mon Aug 05 00:00:00 UTC 2024

The Role of Orai1 in Regulating Sarcoplasmic Calcium Release, Mitochondrial Morphology and Function in Myostatin Deficient Skeletal Muscle.

Frontiers in physiology

Sztretye M,Singlár Z,Balogh N,Kis G,Szentesi P,Angyal Á,Balatoni I,Csernoch L,Dienes B

Mon Aug 05 00:00:00 UTC 2024

The Role of Orai1 in Regulating Sarcoplasmic Calcium Release, Mitochondrial Morphology and Function in Myostatin Deficient Skeletal Muscle.

Frontiers in physiology

Sztretye M,Singlár Z,Balogh N,Kis G,Szentesi P,Angyal Á,Balatoni I,Csernoch L,Dienes B

Mon Aug 05 00:00:00 UTC 2024

生物信息学

蛋白别名: calcium release-activated calcium channel 1; Calcium release-activated calcium channel protein 1; calcium release-activated calcium modulator 1; FLJ14466; Protein orai-1; Transmembrane protein 142A

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基因别名: CRACM1; D730049H07Rik; IMD9; orai-1; ORAI1; ORAT1; RGD1311873; TAM2; TMEM142A

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UniProt ID: (Human) Q96D31, (Rat) Q5M848, (Mouse) Q8BWG9

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Entrez Gene ID: (Human) 84876, (Rat) 304496, (Mouse) 109305

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功能

protein binding calmodulin binding store-operated calcium channel activity identical protein binding calcium channel activity

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