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This antibody detects endogenous protein at a molecular weight of 40 kDa.
Purity is >95% by SDS-PAGE.
Opticin, also known as OPTC or OPT, is a 332 amino acid protein that is secreted into the extracellular matrix and contains seven LRR repeats. Expressed in skin and fetal liver and also present in ocular tissues, such as the retina, cornea and iris, opticin functions to bind collagen fibrils and, via this interaction, is thought to regulate fibril spacing, morphology and organization. Opticin is subject to post-translational O-glycosylation and may be associated with the pathogenesis of primary open angle glaucoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Oculoglycan; Opticin
基因别名: OPT; OPTC
UniProt ID: (Human) Q9UBM4, (Mouse) Q920A0
Entrez Gene ID: (Human) 26254, (Mouse) 269120, (Rat) 304802