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Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Mmgt2 mediates Mg(2+) transport and may provide regulated pathways for Mg(2+) transport in the Golgi and post-Golgi organelles of epithelium-derived cells. Magnesium is an essential metal, but few selective transporters have been identified. The two separate gene products, Mmgt1 and Mmgt2, comprise the family that we have termed membrane Mg(2+) transporters (MMgTs), and the proteins reside in the membrane and mediate Mg(2+) transport. The transport of Mg(2+) is saturable and studies have identified that Mmgt2 fusion proteins reside in the Golgi complex and post-Golgi vesicles, including the early endosomes in COS-7 cells transfected with the respective tagged constructs. Among related pathways for Mmgt2 are transport and binding events, in particular, transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds.
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蛋白别名: ATP receptor; Membrane magnesium transporter 2; membrane magnesium transporter 2 {ECO:0000250|UniProtKB:Q8R3L0}; MGC47755; mmgt2; mmgt2 {ECO:0000250|UniProtKB:Q8R3L0}; P2X purinoceptor 5; P2X5; Purinergic receptor; purinergic receptor P2X5-2
基因别名: AI852046; Mmgt2; P2rx5; P2X5; RGD1311260
UniProt ID: (Rat) Q6P719, (Mouse) Q8R3L0, (Mouse) Q91VE2, (Rat) P51578
Entrez Gene ID: (Rat) 303211, (Mouse) 216829, (Mouse) 94045, (Rat) 113995