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产品信息
PA5-96804
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 240-410 of human PACSIN2 (NP_0091602)
偶联物
形式
Liquid
浓度
0.79 mg/mL
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808606
产品详细信息
Immunogen sequence: RLRFFREVLL EVQKHLDLSN VAGYKAIYHD LEQSIRAADA VEDLRWFRAN HGPGMAMNWP QFEEWSADLN RTLSRREKKK ATDGVTLTGI NQTGDQSLPS KPSSTLNVPS NPAQSAQSQS SYNPFEDEDD TGSTVSEKDD TKAKNVSSYE KTQSYPTDWS DDESNNPFSS T; Positive Samples: BT-474, HepG2, Mouse lung, Mouse heart; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle membrane, Early endosome, Membrane, Peripheral membrane protein, Recycling endosome membrane, caveola, cytoskeleton, ruffle membrane
靶标信息
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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