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Peptide sequence: DLAEALVDFI YQYWKLKRKA NANQPLLTPK TDEVDNLAQQ EQDVLYRRLK
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase Jade-2; Jade family PHD finger protein 2; PHD finger protein 15
基因别名: JADE-2; JADE2; KIAA0239; PHF15
UniProt ID: (Human) Q9NQC1
Entrez Gene ID: (Human) 23338