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PLB1 Antibody (PA5-120091) in WB
Western blot analysis of PLB1 in extracts of various cell lines. Samples were incubated with PLB1 Polyclonal antibody (Product # PA5-120091) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-120091
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1110-1415 of human PLB1 (NP_694566.4).
偶联物
形式
Liquid
浓度
1.56 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2913663
产品详细信息
Positive test controls include: A-431, U-87MG, HL-60, HT-29, Mouse testis, Mouse lung, Mouse skeletal muscle, Rat testis. The target is usually found in the following locations: Apical cell membrane, Single-pass type I membrane protein.
Immunogen sequence: ARPNNSSDLP TSWRGLSWSI GGDGNLETHT TLPNILKKFN PYLLGFSTST WEGTAGLNVA AEGARARDMP AQAWDLVERM KNSPDINLEK DWKLVTLFIG VNDLCHYCEN PEAHLATEYV QHIQQALDIL SEELPRAFVN VVEVMELASL YQGQGGKCAM LAAQNNCTCL RHSQSSLEKQ ELKKVNWNLQ HGISSFSYWH QYTQREDFAV VVQPFFQNTL TPLNERGDTD LTFFSEDCFH FSDRGHAEMA IALWNNMLEP VGRKTTSNNF THSRAKLKCP SPESPYLYTL RNSRLLPDQA EEAPEV
靶标信息
This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Lysophospholipase; Phospholipase A2; Phospholipase B; Phospholipase B/lipase; Phospholipase B1, membrane-associated; PLB/LIP; Triacylglycerol lipase
基因别名: 4632413E21Rik; 4930433E17Rik; 4930539A06Rik; BC033606; hPLB; Phlpb; PLB; PLB/LIP; PLB1
UniProt ID: (Human) Q6P1J6, (Rat) O54728, (Mouse) Q3TTY0
Entrez Gene ID: (Human) 151056, (Rat) 192259, (Mouse) 665270
