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PXK is widely expressed in all tissues examined except in heart. It binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. However, the protein kinase domain is predicted to be catalytically inactive.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Modulator of Na,K-ATPase; modulator of Na,K-ATPase long form; MONaKA; PX domain-containing protein kinase-like protein; PX ser/thr kinase v2; PX serine/threonine kinase; PXK; pxk {ECO:0000312|EMBL:AAP92800.1, ECO:0000312|RGD:727819}
基因别名: C230080L11Rik; D14Ertd813e; MONaKA; PXK
UniProt ID: (Human) Q7Z7A4, (Mouse) Q8BX57, (Rat) Q4FZZ1
Entrez Gene ID: (Human) 54899, (Mouse) 218699, (Rat) 306203