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Phospho-Paxillin (Ser178) Antibody (A300-100A) in WB
Detection of mouse phospho Paxillin (Ser178) by western blot. Samples: Whole cell lysate (approximately 2.4 x 10^5 cells/lane) from NIH3T3 cells that were serum starved for 16 hours and then grown in suspension culture or plated on fibronectin (50 µg/ml). Whole cell lysate from cells grown on fibronectin was untreated or treated with lambda phosphatase. Antibody: Affinity purified rabbi... View More
产品信息
A300-100A
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Surrounding serine 178
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Human and Rat
靶标信息
Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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