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Phospho-SMC1 (Ser957) Antibody (A300-045A-T) in WB
Detection of human Phospho SMC1 (S957) by western blot. Samples: Whole cell lysate (50 µg) from 293T cells that were mock treated (-) or treated with 100 µM Etoposide (+) for 4 hours. Antibody: Affinity purified rabbit anti-Phospho SMC1 (S957) antibody A300-045A-M (lot A300-045A-M-3) used at 1:1000. Detection: Chemiluminescence with an exposure time of 3 minutes.
产品信息
A300-045A-T
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Surrounding serine 957
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine
靶标信息
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregatior defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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