Invitrogen

Phospho-WEE1 (Ser642) Monoclonal Antibody (T.870.10)

产品信息

MA5-14806

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

-

免疫沉淀 (IP)

1:50

-

产品规格

种属反应

Bovine, Human, Mouse, Non-human primate, Rat, Xenopus, Zebrafish

宿主/亚型

Rabbit / IgG

分类

Monoclonal

类型

Antibody

克隆号

T.870.10

抗原

Synthetic phosphopeptide corresponding to residues surrounding pSer642 of human wee1

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

纯化类型

Affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

内含物

<0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

RRID

AB_10976933

产品详细信息

It is not recommended to aliquot this antibody.

靶标信息

WEE1, which is classified as a Ser/Thr kinase by sequence analysis, has been shown to inactivate multiple CDKs by tyrosine phosphorylation. Wee1 protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: DKFZp686I18166; FLJ16446; wee 1 homolog; WEE1 homolog; WEE1 tyrosine kinase; WEE1+ homolog; Wee1-like protein kinase; Wee1A kinase; WEE1hu

查看更多收起

基因别名: BOS_14491; fa20h03; WEE1; WEE1A; WEE1hu; wu:fa20h03; zgc:136514

查看更多收起

UniProt ID: (Human) P30291, (Mouse) P47810, (Rat) Q63802

查看更多收起

Entrez Gene ID: (Bovine) 540322, (Human) 7465, (Mouse) 22390, (Rat) 308937, (Zebrafish) 327060

查看更多收起

magnesium ion binding protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding kinase activity nucleotide binding protein kinase activity transferase activity transferase activity, transferring phosphorus-containing groups metal ion binding protein serine/threonine kinase activity

参与通路

mitotic cell cycle protein phosphorylation response to light stimulus phosphorylation microtubule cytoskeleton organization cell cycle mitotic nuclear division peptidyl-tyrosine phosphorylation establishment of cell polarity neuron projection morphogenesis cell division G2/M transition of mitotic cell cycle regulation of cell cycle