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Immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Antigen; Gamma-seminoprotein; Kallikrein 3; Kallikrein-3; Kallikrein-3 (KLK3); kallikrein-related peptidase 3; KLK-3; P-30 antigen; prostate specific antigen; prostate-specific (APS); Prostate-specific antigen; PSA; Semenogelase; Seminin
基因别名: APS; hK3; KLK2A1; KLK3; PSA
UniProt ID: (Human) P07288
Entrez Gene ID: (Human) 354