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产品信息
MA1-35782
应用
建议稀释比
已发表文章
产品规格
种属反应
Goat,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
已发表种属
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
G4E4
抗原
Human retinol binding protein (RBP) purified from plasma
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
purified
保存液
PBS
内含物
0.02% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2179286
产品详细信息
G4E4 recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.
靶标信息
This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: C CRABP-I; cellular retinol binding protein 1; Cellular retinol-binding protein; Cellular retinol-binding protein I; CRBP; CRBP-I; mCRBPI; RBP; retinol; retinol binding; Retinol Binding Protein; retinol binding protein 1, cellular-like; Retinol-binding protein 1; retinol-binding protein 1, cellular
基因别名: CRABP-I; CRBP; CRBP1; CRBPI; Rbp-1; RBP1; RBPC
UniProt ID: (Human) P09455, (Mouse) Q00915, (Rat) P02696
Entrez Gene ID: (Rabbit) 100354448, (Human) 5947, (Mouse) 19659, (Rat) 25056
