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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.
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蛋白别名: epididymis secretory protein Li 84; FLJ37041; proliferation-inducing gene 20; reticulocalbin 1, EF-hand calcium binding domain; Reticulocalbin-1
基因别名: HEL-S-84; PIG20; Rca1; RCAL; RCN; RCN1
UniProt ID: (Human) Q15293, (Mouse) Q05186
Entrez Gene ID: (Human) 5954, (Mouse) 19672