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产品信息
PA5-76399
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein of human RPP30.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720126
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
RNase P, which consists of a complex of an RNA species (H1 RNA), POP1 (Processing of Precursor 1), POP5 (Processing of Precursor 5), and at least seven Rpps (including Rpp14, Rpp29, Rpp30 and Rpp38), removes the 5' leader sequences from precursor tRNA molecules. The structurally related RNase MRP plays an essential role in the formation of the 5' end of 5.8S rRNA. Both RNase P and RNase MRP are associated with Th/To ribonucleoproteins; Rpp30 and Rpp38 have specifically been implicated as Th autoantigens which contribute to the autoimmune disease systemic sclerosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Ribonuclease P protein subunit p30; ribonuclease P/MRP 30kDa subunit; ribonuclease P/MRP subunit; ribonuclease P2; RNase P subunit 2; RNaseP protein p30
基因别名: RNASEP2; RPP30; TSG15
UniProt ID: (Human) P78346, (Mouse) O88796
Entrez Gene ID: (Human) 10556, (Rat) 685332, (Mouse) 54364
