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产品信息
PA5-22117
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 1 and 62 of SENP2 (Uniprot ID#Q9HC62)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol, 1% BSA
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11154629
产品详细信息
Recommended positive controls: 293T, Molt-4.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Axam2; CT; Sentrin-specific protease 2; Sentrin/SUMO-specific protease SENP2; SMT3-specific isopeptidase 2; Smt3ip2; SUMO1/sentrin/SMT3 specific protease 2
基因别名: AXAM2; KIAA1331; SENP2; SMT3IP2
UniProt ID: (Human) Q9HC62
Entrez Gene ID: (Human) 59343
positive regulation of protein phosphorylation
heart development
dorsal/ventral axis specification
protein transport
Wnt signaling pathway
protein sumoylation
protein desumoylation
regulation of Wnt signaling pathway
negative regulation of protein ubiquitination
positive regulation of protein ubiquitination
protein destabilization
negative regulation of protein binding
regulation of DNA endoreduplication
negative regulation of chromatin binding
negative regulation of DNA damage response, signal transduction by p53 class mediator
fat cell differentiation
positive regulation of transcription from RNA polymerase II promoter
mRNA transport
trophoblast giant cell differentiation
labyrinthine layer development
spongiotrophoblast layer development
regulation of G1/S transition of mitotic cell cycle
