Invitrogen

SGMS2 Polyclonal Antibody

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SGMS2 Antibody (PA5-26744) in WB

Western blot analysis was performed on whole cell extracts of HEK 293 (Lane 1), U-2 OS (Lane 2), SK-OV-3 (Lane 3), Hep G2 (Lane 4), Caco-2 (Lane 5), MCF7 (Lane 6), tissue extracts of Mouse Liver (Lane 7) and Mouse Heart (Lane 8). The blot was probed with Anti-SGMS2 Polyclonal Antibody (Product # PA5-26744, 1:1,000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4,000 dilution). A 50 kDa band corresponding to SGMS2 was observ... View More

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产品信息

PA5-26744

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 338-365 amino acids from the C-terminal region of human SGMS2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A, Antigen affinity chromatography

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2544244

产品详细信息

This antibody is predicted to react with non-human primate and rat based on sequence homology.

靶标信息

A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.

仅用于科研。不用于诊断过程。未经明确授权不得转售。