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SMARCC1 Antibody (MA5-34657) in ICC/IF
Immunofluorescence analysis of SMARCC1 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with SMARCC1 Recombinant Rabbit Monoclonal Antibody (JB43-43) (Product # MA5-34657) at 1:100 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa F... View More
产品信息
MA5-34657
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JB43-43
抗原
Recombinant protein within Human SMARCC1 aa 680-820
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Wet ice
RRID
AB_2848565
产品详细信息
Positive Control: Mouse thymus tissue, HL-60, 293T, mouse testis tissue, K562.
靶标信息
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BAF155; BRG1-associated factor 155; chromatin remodeling complex BAF155 subunit; mammalian chromatin remodeling complex BRG1-associated factor 155; SWI/SNF complex 155 kDa subunit; SWI/SNF complex subunit SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1; SWI3-related protein
基因别名: AI115498; BAF155; CRACC1; Rsc8; SMARCC1; SRG3; SWI3
UniProt ID: (Human) Q92922, (Mouse) P97496
Entrez Gene ID: (Human) 6599, (Mouse) 20588
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
transcription coactivator activity
protein binding
nucleosomal DNA binding
protein N-terminus binding
DNA binding
chromatin binding
chromatin/chromatin-binding, or -regulatory protein
nucleosome disassembly
chromatin remodeling
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
insulin receptor signaling pathway
organ morphogenesis
covalent chromatin modification
prostate gland development
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
ATP-dependent chromatin remodeling
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
DNA packaging
regulation of transcription, DNA-templated
chromatin modification
