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SMC2 Antibody (PA5-110399) in WB
Western blot analysis of SMC2 in extracts of various cells. Samples were incubated with SMC2 Polyclonal antibody (Product # PA5-110399) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-110399
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 700-900 of human SMC2 (NP_006435.2).
偶联物
形式
Liquid
浓度
0.66 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855810
产品详细信息
Immunogen sequence: EELAGLKNTA EKYRQLKQQW EMKTEEADLL QTKLQQSSYH KQQEELDALK KTIEESEETL KNTKEIQRKA EEKYEVLENK MKNAEAERER ELKDAQKKLD CAKTKADASS KKMKEKQQEV EAITLELEEL KREHTSYKQQ LEAVNEAIKS YESQIEVMAA EVAKNKESVN KAQEEVTKQK EVITAQDTVI KAKYAEVAKH K
靶标信息
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behavior of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in humar cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAP E; Chromosome-associated protein E; FGF-inducible protein 16; fibroblast growth factor inducible 16; FLJ10093; hCAP-E; SMC protein 2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 protein; SMC2 structural maintenance of chromosomes 2-like 1; structural maintenance of chromosomes (SMC) family member, chromosome-associated protein E; Structural maintenance of chromosomes protein 2; XCAP-E homolog
基因别名: 5730502P04Rik; AI255214; AW545314; CAP-E; CAPE; Fin16; PRO0324; SMC-2; SMC2; SMC2L1
UniProt ID: (Human) O95347, (Mouse) Q8CG48
Entrez Gene ID: (Human) 10592, (Mouse) 14211
