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SMPD2 Antibody (PA5-24614) in WB
Western blot analysis of SMPD2 in various lysates. Samples were incubated with SMPD2 polyclonal antibody (Product # PA5-24614) using a dilution of 1:1,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: K562 whole cell lysate; Lane 2: SH-SY5Y whole cell lysate. Predicted band size: 48 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
PA5-24614
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 9-35 amino acids from the N-terminal region of human SMPD2
偶联物
形式
Liquid
浓度
1.8 mg/mL
纯化类型
Ammonium sulfate precipitation, Size-exclusion - Dialysis
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2542114
靶标信息
Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Lyso-PAF-PLC; Lyso-platelet-activating factor-phospholipase C; N-SMase; Neutral sphingomyelinase; neutral sphingomyelinase 1; NSMA; Sphingomyelin phosphodiesterase 2; sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
基因别名: AW108287; ISC1; NSMASE; NSMASE1; SMPD2
UniProt ID: (Human) O60906, (Mouse) O70572
Entrez Gene ID: (Human) 6610, (Mouse) 20598
sphingomyelin metabolic process
glycosphingolipid metabolic process
response to mechanical stimulus
intracellular signal transduction
ceramide biosynthetic process
positive regulation of ceramide biosynthetic process
lipid metabolic process
sphingolipid metabolic process
positive regulation of apoptotic process
