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产品信息
PA5-55656
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2647744
产品详细信息
Immunogen sequence: DSSPLLNEVS SSLIGTDSQA FPSVSKPSSA YPSTTIVNPT IVLLQHNREQ QKRLSSLSDP VSERRVGEQD SAPTQEKPTS PGKAIEKRAK DDSRRVVKST QDLSDVSMDE VGIPLRNTER SKDWYKTMFK QIHKLNR
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 85%.
靶标信息
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: c-Cbl associated protein; c-Cbl-associated protein; CAP; DKFZp451C066; DKFZP586P1422; Fas-ligand associated factor 2; FLJ12406; OTTHUMP00000020142; OTTHUMP00000020143; OTTHUMP00000020144; OTTHUMP00000020145; Ponsin; SH3 domain protein 5; SH3P12; Sorbin and SH3 domain-containing protein 1; SORBS1
基因别名: CAP; FLAF2; KIAA0894; KIAA1296; R85FL; SH3D5; SH3P12; SORB1; SORBS1
UniProt ID: (Human) Q9BX66
Entrez Gene ID: (Human) 10580
muscle contraction
cell-matrix adhesion
insulin receptor signaling pathway
positive regulation of signal transduction
glucose transport
cellular response to insulin stimulus
stress fiber assembly
positive regulation of glycogen biosynthetic process
positive regulation of glucose import
positive regulation of lipid biosynthetic process
focal adhesion assembly
positive regulation of establishment of protein localization to plasma membrane
