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产品信息
PA5-112860
产品规格
种属反应
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Zebrafish HMG-box transcription factor Sox10 protein (1-485AA)
偶联物
形式
Liquid
浓度
5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2867594
靶标信息
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cls; colorless; colourless; colourless/sox10; golas; gos; MGC15649; sox10b; SRY; SRY (sex determining region Y)-box 10; SRY-box containing gene 10
基因别名: cls/sox10; zgc:100757
Entrez Gene ID: (Zebrafish) 140616
negative regulation of transcription from RNA polymerase II promoter
neural crest cell migration
morphogenesis of an epithelium
peripheral nervous system development
glial cell differentiation
positive regulation of gene expression
neural crest cell development
Schwann cell differentiation
Schwann cell development
olfactory bulb development
glial cell development
myelination in peripheral nervous system
melanocyte differentiation
pigmentation
positive regulation of transcription from RNA polymerase II promoter
developmental pigmentation
enteric nervous system development
oligodendrocyte differentiation
semicircular canal morphogenesis
inner ear development
otolith development
negative regulation of neurogenesis
pigment cell differentiation
retina development in camera-type eye
otic vesicle morphogenesis
cranial skeletal system development
