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SRC Family Negative Regulatory (pY) Site Antibody (44-912) in WB
Extracts prepared from PC12 cells treated with 0.5 M sorbitol for 5 minutes were resolved by SDS-PAGE on a 10% polyacrylamide gel and transferred to PVDF. Membranes were blocked with a 5% BSA-TBST buffer overnight at 4oC, then were incubated with 0.50 µg/.
产品信息
44-912
应用
建议稀释比
已发表文章
产品规格
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthesized phosphopeptide derived from the region of human Hck that contains tyrosine 522.
偶联物
形式
Liquid
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2533793
靶标信息
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
