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产品信息
PA5-72988
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide made to an internal portion of the human SUV420h1 protein (between residues 100-150) [UniProt Q4FZB7]
偶联物
形式
Liquid
浓度
1.14 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 30% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2718842
靶标信息
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [histone H4]-lysine20 N-methyltransferase KMT5B; [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; C630029K18Rik; Histone-lysine N-methyltransferase KMT5B; histone-lysine N-methyltransferase SUV420H1; lysine (K)-specific methyltransferase 5B; Lysine N-methyltransferase 5B; Lysine-specific methyltransferase 5B; MGC118906; MGC118909; MGC21161; MGC703; Su(var)4-20 homolog 1; Suppressor of variegation 4-20 homolog 1; suv4-20h1; SUV420
基因别名: AA117471; C630029K18Rik; CGI-85; CGI85; KMT5B; Suv4-20h1; SUV420H1
UniProt ID: (Human) A0A0A0MT19, (Mouse) Q3U8K7
Entrez Gene ID: (Human) 51111, (Mouse) 225888
