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产品信息
PA5-43678
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human TAF3
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2607437
产品详细信息
Peptide sequence: RDREREKDKN KDKSKEKDKV KEKEKDKETG RETKYPWKEF LKEEEADPYK
Sequence homology: Cow: 79%; Dog: 79%; Guinea Pig: 92%; Human: 100%; Rabbit: 92%; Rat: 92%; Yeast: 79%; Zebrafish: 85%
靶标信息
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process. Belongs to the TFIID complex which is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with TAF10 via the histone fold. Interacts with TAF13, TBP, SAP130 and GCN5L2. Interacts with TBPL2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 140 kDa TATA box-binding protein-associated factor; MGC25063; RNA polymerase II transcription factor TAFII140; TAF(II)140; TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa; TATA box binding protein associated factor 3; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; Transcription initiation factor TFIID subunit 3
基因别名: TAF140; TAF3; TAFII-140; TAFII140
UniProt ID: (Human) Q5VWG9
Entrez Gene ID: (Human) 83860
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
negative regulation of sequence-specific DNA binding transcription factor activity
maintenance of protein location in nucleus
regulation of signal transduction by p53 class mediator
