Search Thermo Fisher Scientific
Sequence of this protein is as follows: STLLQGTGNG VPATHPHLLS GSSCSSPAFH LGPNTSQLCS LAPADYSACA RSGLTLNRYS TSLAETYNRL TNQAGETFAP PRTPSYVGVS SSTSVNMSMG GTDGDTF
The T-box (Tbx) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The Tbx gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. Tbx genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in Tbx genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/Brachyury, which is a transcription activator. The Tbx genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: T-box protein 14; T-box protein 15; T-box protein 18; T-box transcription factor TBX18; TBX14; TBX15
基因别名: 2810012F10Rik; 2810404D13Rik; CAKUT2; TBX18
UniProt ID: (Human) O95935, (Mouse) Q9EPZ6
Entrez Gene ID: (Human) 9096, (Rat) 315870, (Mouse) 76365