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产品信息
PA5-52582
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2648298
产品详细信息
Immunogen sequence: IPMPTFGGLF PYPYTYMAAA AAAASALPAT SAAAAAAAAA GSLSRSPFLG SARPRLRFSP YQIPVTIPPS TSLLTTGLAS EGSKAAGGNS REPSPLPELA LRKVGAPSRG ALSPSGSAKE AANELQSIQR LVSGL
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 49%.
靶标信息
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ10169; T-box protein 2; T-box transcription factor TBX2
基因别名: TBX2
UniProt ID: (Human) Q13207
Entrez Gene ID: (Human) 6909
negative regulation of transcription from RNA polymerase II promoter
heart looping
outflow tract septum morphogenesis
outflow tract morphogenesis
endocardial cushion morphogenesis
regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
transcription, DNA-templated
Notch signaling pathway
muscle cell fate determination
cell aging
regulation of heart contraction
positive regulation of cell proliferation
embryonic heart tube development
aorta morphogenesis
atrioventricular canal development
embryonic digit morphogenesis
negative regulation of transcription, DNA-templated
embryonic camera-type eye morphogenesis
cardiac muscle tissue development
palate development
positive regulation of cardiac muscle cell proliferation
pharynx development
developmental growth involved in morphogenesis
mammary placode formation
cellular senescence
negative regulation of heart looping
negative regulation of cardiac chamber formation
