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This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Mitochondrial import inner membrane translocase subunit TIM44; translocase of inner mitochondrial membrane 44 homolog; translocator of inner mitochondrial membrane 44
基因别名: MIMT44; TIM44; TIMM44
UniProt ID: (Human) O43615, (Rat) O35094
Entrez Gene ID: (Human) 10469, (Rat) 29635