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产品信息
PA5-34554
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
An 18 amino acid peptide near the amino terminus of human TLX2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551906
产品详细信息
A suggested positive control is rat brain tissue lysate.
PA5-34554 can be used with blocking peptide PEP-1597.
靶标信息
The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX2, also known as homeobox11-like 1 (HOX11L1), is a DNA-binding nuclear transcription factor that appears to be crucial for the development of the peripheral nervous system. TLX2 is a downstream target of regulation by both PHOX2A and PHOX2B proteins during intestinal neuronal differentiation. In humans, loss-of-function of TLX2 may play a role in tumorigenesis of gastrointestinal stromal tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Enteric neuron homeobox protein; homeo box 11-like 1; homeobox 11-like1; Homeobox protein Hox-11L1; Homeobox TLX-2; Hox11L.1; Neural crest homeobox protein; PMUR10F; T-cell leukemia homeobox protein 2; T-cell leukemia, homeobox 2
基因别名: Enx; Hox11L.1; HOX11L1; NCX; Ncx1; Tlx1l1; Tlx1l2; TLX2
UniProt ID: (Human) O43763, (Mouse) Q61663
Entrez Gene ID: (Human) 3196, (Rat) 680117, (Mouse) 21909
