Invitrogen

TOB1 Polyclonal Antibody

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TOB1 Antibody (PA5-68791) in WB

Western blot analysis of TOB1 on mouse NIH-3T3 cells. The sample was probed with a TOB1 polyclonal antibody (Product # PA5-68791) using a primary antibody dilution of 1.25 µg/mL.

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产品信息

PA5-68791

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1.25 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

synthetic peptide directed towards the middle region of mouse TOB1

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.0 mg/mL

纯化类型

Protein A

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

RRID

AB_2691407

产品详细信息

This target displays homology in the following species: Cow: 93%; Dog: 93%; Horse: 93%; Human: 93%; Mouse: 100%; Pig: 93%; Rat: 93%

靶标信息

This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。