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TRIM8 Antibody (H00081603-B01P) in WB
Western Blot analysis of TRIM8 expression in transfected 293T cell line (H00081603-T01) by TRIM8 MaxPab polyclonal antibody.
Lane 1: TRIM8 transfected lysate(60.61 KDa).
Lane 2: Non-transfected lysate.
Lane 1: TRIM8 transfected lysate(60.61 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00081603-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
TRIM8 (AAH21925.1, 1 a.a. approximately 551 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MAENWKNCFE EELICPICLH VFVEPVQLPC KHNFCRGCIG EAWAKDSGLV RCPECNQAYN QKPGLEKNLK LTNIVEKFNA LHVEKPPAAL HCVFCRRGPP LPAQKVCLRC EAPCCQSHVQ THLQQPSTAR GHLLVEADDV RAWSCPQHNA YRLYHCEAEQ VAVCQYCCYY SGAHQGHSVC DVEIRRNEIR KMLMKQQDRL EEREQDIEDQ LYKLESDKRL VEEKVNQLKE EVRLQYEKLH QLLDEDLRQT VEVLDKAQAK FCSENAAQAL HLGERMQEAK KLLGSLQLLF DKTEDVSFMK NTKSVKILMD RTQTCTSSSL SPTKIGHLNS KLFLNEVAKK EKQLRKMLEG PFSTPVPFLQ SVPLYPCGVS SSGAEKRKHS TAFPEASFLE TSSGPVGGQY GAAGTASGEG QSGQPLGPCS STQHLVALPG GAQPVHSSPV FPPSQYPNGS AAQQPMLPQY GGRKILVCSV DNCYCSSVAN HGGHQPYPRS GHFPWTVPSQ EYSHPLPPTP SVPQSLPSLA VRDWLDASQQ PGHQDFYRVY GQPSTKHYVT S
靶标信息
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase TRIM8; glioblastoma expressed ring finger protein; Glioblastoma-expressed RING finger protein; RING finger protein 27; RING-type E3 ubiquitin transferase TRIM8; tripartite motif protein TRIM8; tripartite motif-containing 8; Tripartite motif-containing protein 8
基因别名: GERP; RNF27; TRIM8
UniProt ID: (Human) Q9BZR9
Entrez Gene ID: (Human) 81603
positive regulation of autophagy
protein ubiquitination
stem cell population maintenance
negative regulation of viral transcription
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
negative regulation of viral entry into host cell
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
interferon-gamma-mediated signaling pathway
positive regulation of protein localization to nucleus
negative regulation of viral release from host cell
