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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAGSGCAWGA EPPRFLEAFG RLWQVQSRLG SGSSASVYRV RCCGNPGSPP GALKQFLPPG TTGAAASAAE YGFRKERAAL EQLQGHRNIV TLYGVFTIHF SPNVPSRCLL LELLDVSVSE LLLYSSHQGC SMWMIQHCAR DVLEALAFLH HEGYVHADLK PRNILWSAEN ECFKLIDFGL SFKEGNQDVK YIQTDGYRAP EAELQNCLAQ AGLQSDTECT SAVDLWSLGI ILLEMFSGMK LKHTVRSQEW KANSSATIDH IFASKAVVNA AIPAYHLRDL IKSMLHDDPS RRIPAEMALC SPFFSIPFAP HIEDLVMLPT PVLRLLNVLD DDYLENEEEY EGLC
Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: kinase interacting with leukemia-associated gene (stathmin); Kinase interacting with stathmin; KIS protein kinase; P-CIP2; PAM COOH-terminal interactor protein 2; Serine/threonine-protein kinase Kist; U2AF homology motif kinase 1
基因别名: KIS; KIST; P-CIP2; UHMK1
UniProt ID: (Human) Q8TAS1
Entrez Gene ID: (Human) 127933