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Antibody detects endogenous levels of total USP45.
The protein encoded by this gene is a deubiquitylase that binds ERCC1, the catalytic subunit of the XPF-ERCC1 DNA repair endonuclease. This endonuclease is a critical regulator of DNA repair processes, and the deubiquitylase activity of the encoded protein is important for maintaining the DNA repair ability of XPF-ERCC1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Deubiquitinating enzyme 45; granule cell antiserum positive 7; Ubiquitin carboxyl-terminal hydrolase 45; ubiquitin specific petidase 45; ubiquitin specific protease 45; Ubiquitin thioesterase 45; ubiquitin thiolesterase 45; Ubiquitin-specific-processing protease 45
基因别名: 3110003C05Rik; 4930550B20Rik; AI843191; Gcap7; USP45
UniProt ID: (Human) Q70EL2, (Mouse) Q8K387
Entrez Gene ID: (Human) 85015, (Rat) 313098, (Mouse) 77593