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产品信息
MA5-29786
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
030
抗原
Recombinant Human Uteroglobin/SCGB1A1 protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2785608
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human Uteroglobin/SCGB1A1.
靶标信息
Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: blastokinin; CC10; CCPBP; clara cell phospholipid-binding protein; clara cells 10 kDa secretory protein; Club cell phospholipid-binding protein; Club cells 10 kDa secretory protein; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UP-1; Urinary protein 1; urine protein 1; Uteroglobin
基因别名: CC10; CC16; CCPBP; CCSP; SCGB1A1; UGB; UP-1; UP1
UniProt ID: (Human) P11684
Entrez Gene ID: (Human) 7356
negative regulation of transcription from RNA polymerase II promoter
signal transduction
female pregnancy
embryo implantation
response to xenobiotic stimulus
response to ozone
response to lipopolysaccharide
negative regulation of interferon-gamma production
negative regulation of interleukin-13 production
negative regulation of interleukin-4 production
negative regulation of interleukin-5 production
response to silicon dioxide
response to cytokine
negative regulation of T cell proliferation
response to drug
negative regulation of catalytic activity
regulation of mRNA stability
regulation of inflammatory response
response to glucocorticoid
response to fibroblast growth factor
