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产品信息
PA5-21089
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 17 amino acid peptide near the carboxy terminus of human ZMYM1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152833
产品详细信息
A suggested positive control is rat lung tissue lysate.
PA5-21089 can be used with blocking peptide PEP-1203.
靶标信息
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RP11-181E22.4; RP11-248I9.4; Zinc finger MYM-type protein 1; zinc finger, MYM domain containing 1; zinc finger, MYM-type 1
基因别名: 5830412B09Rik; AW209050; MYM; ZMYM1
UniProt ID: (Human) Q5SVZ6
Entrez Gene ID: (Human) 79830, (Rat) 313604, (Mouse) 68310
