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产品信息
PA5-51286
产品规格
种属反应
Human
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide of human DEFB1
偶联物
形式
Liquid
浓度
1.9 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2636733
产品详细信息
The antibody detects endogenous levels of total DEFB1 protein.
靶标信息
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BD-1; beta defensin 1; Beta-defensin 1; beta-defensin-1; Defensin, beta 1
基因别名: BD1; DEFB-1; DEFB1; DEFB101; HBD1
UniProt ID: (Human) P60022
Entrez Gene ID: (Human) 1672
innate immune response in mucosa
acute inflammatory response
chemotaxis
immune response
G-protein coupled receptor signaling pathway
response to bacterium
antibacterial humoral response
cAMP-mediated signaling
response to testosterone
calcium-mediated signaling using intracellular calcium source
defense response to bacterium
innate immune response
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
positive regulation of sperm motility involved in capacitation
