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产品信息
AGC-026-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)GQSDDSTRK(S)TGEE, corresponding to amino acid residues 368-381 of rat mGluR6, Extracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor GRM6; G protein-coupled receptor, family C, group 1, member F; glutamate receptor; glutamate receptor, metabotropic 6; Metabotropic glutamate receptor 6; mGluR6
基因别名: BC021919; CSNB1B; Gm3; GPRC1F; GRM6; mGlu6; MGLUR6; nerg1; nob2; nob3; nob4
UniProt ID: (Human) O15303, (Rat) P35349, (Mouse) Q5NCH9
Entrez Gene ID: (Human) 2916, (Rat) 24419, (Mouse) 108072
adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
locomotory behavior
detection of visible light
detection of light stimulus involved in visual perception
regulation of synaptic transmission, glutamatergic
retina development in camera-type eye
positive regulation of calcium ion import
signal transduction
sensory perception of light stimulus
G-protein coupled receptor signaling pathway
visual perception
response to stimulus
