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Chicken IL-12 p40 quantitates chicken IL-12 p40 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant chicken IL-12 p40.
IL12B (IL-12 p40) encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kDa cytokine receptor like subunit encoded by this gene, and a 35 kDa subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : IL-12B, IL-12p40
基因ID : (Chicken) 404671
基因符号 : IL12B
蛋白别名 : CLMF p35, IL-12 subunit p35, IL12A, IL-12A, NKSF1, RP23-388G23.1, Interleukin, Interleukin 12, Interleukin12, il 12, IL12 p40, ILN, IL-12 p40 subunit, interleukin-12 beta chain, interleukin-12 p40 subunit, interleukin-12 subunit beta, interleukin-12p40