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The Human Follistatin (Hu FST) ELISA quantitates Hu FST in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu FST.
原理方法
The Human FST solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : FS, FST
基因ID : (Human) 10468
基因符号 : FST
蛋白别名 : Activin-binding protein, Follistatin, follistatin isoform FST317, FS, Follictatin
UniProt ID (Human) P19883