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产品规格
检测灵敏度
0.41 ng/mL
测定范围
0.41-100 ng/mL
检测样本类型/体积
{Supernatant=50 µL, Plasma=50 µL, Serum=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Colorimetric Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
2-8°C
蛋白名称
VEGF Receptor 1
均相（无需洗涤）
Rat
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Rat VEGFR1 quantitates rat VEGFR1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat VEGFR1.
靶标信息
FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis. Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : VEGFR-1
基因ID : (Rat) 54251
基因符号 : Flt1
蛋白别名 : FLT-1, FMS-like tyrosine kinase 1, Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor), i21, soluble VEGFR 1, sVEGFR 1, VEGF R1, tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, vascular endothelial growth factor receptor-1
